Albert Claude : contributed to medicine by brilliant discovery (1) ⬆️

” It is the cells which create and maintain in us, during the span of our lives, our will to live and survive, to search and experiment, and to struggle.” –  Albert Claude. 

 writer : jotsna jari

❤️ Albert Claude  🔼

(24 August 1899 – 22 May 1983) was a Belgian-American cell biologist & Medical Doctor.

💛 The Nobel Prize in Physiology or 

Medicine 1974.

Prize motivation: “for their discoveries concerning the structural and functional organization of the cell.”

Work :- 

Our bodies are made up of cells that contain organelles, components with various functions. Around 1945 Albert Claude conducted a number of trailblazing studies of cellular components. He made use of the newly developed electron microscope, which enabled him to capture images with a level of detail not previously available. Claude also developed methods for separating the various parts of pulverized cells with a centrifuge so they could be better studied. This also became a breakthrough for cell biology.

💜 Albert Claud’s own writing

about the Life :- 

I was born in Belgium, in 1899. Longlier, my birthplace, is located in a high point of the Belgian Ardennes, atop the rising spur of an eroded remnant of the foot of the Alps, next to a deep valley. In the Middle Ages, it had been a fortified place, of the Francs and Carolegian dynasties. Pepin le Bref, crowned King of the Francs in 751 spent in Longlier two winters, from October to Easter, in the years 750 and 763. His son Charlemagne who by then had become Emperor of the Occident called a High Court of Justice of the Empire to meet in Longlier: the diploma, still preserved, was signed by him there in 771. In the year 1050, the Charlemagne Villa became a Monastery, and renamed later “Ferme Charlemagne”. In the 17th-18th century, it was adorned with a high sloping roof “à la mansarde”, whereas the round towers, standing high at the wall corners, matched the roof with elegant, bell-shaped tops, a situation which remained unchanged until 1914.

The landscape of the Longlier region is covered with remnants of the primeval forest of oak trees, progressively invaded by evergreens. The bluegreen color of the pines, which blends with the blue-grey color of the massif of slate rocks emerging through a meager soil gives the countryside an aspect, severe, but also of serene beauty, and even more, when the pure coat of the snow covers it during the long and cold winters.

. ( continuous…   )

💙

The First Anthropologist & The Father of Indology :  Al Biruni helped rediscover India’s rich past & triggered a cultural awakening ⬆️

 An imaginary rendition of Al Biruni on a       1973 Soviet postage stamp

writer : jotsna jari

.

💚 Al Biruni  💛

(4 September 973 AD, Uzbekistan –

13 December 1048, Afghanistan )

He is a scholar and polymath during the Islamic Golden Age. He has been called variously the “founder of Indology,  “

Father of Comparative Religion, Father of modern Geodesy, and the first Anthropologist. 

Al Biruni & India 💙

Alberuni was 44 years of age when he came to India with Mahmud of Ghazni.

💛 Al-Beruni and the Kitab al-Hind :- 

In his book Tahqiq-i-Hind(Kitab al-Hind),

he described the social, political, religious and economic condition of India. In his account he highlights choice parts of the Gita, the Upanishads, Patanjali, Puranas, the four Vedas, scientific texts (by Nagarjuna, Aryabhata, etc.), relating stories from Indian mythology to make his point.

Alberuni unreservedly praised In­dian philosophy. He was particularly impressed by the Upanishads and the Bhagavad-Gita.

His book is a survey of India’s life based on his studies and observations in India between 1017 and 1030.

Social Condition : – 

  • Indian society was cast-ridden. 
  • Several evil prac­tices like child marriage, prohibition of widow marriage, ‘Sati’ and ‘Jauhar’ existed in the Hindu society. 
  • He does not mention the system of dowry but he writes about the StreeDhan which the relatives of girls present to her in-laws.

Political Condition : – 

  • The entire country was divided into small states which occasionally used to quarrel among themselves. These states were jealous of each other and constantly engaged in fights against one another. Malwa, Sindh, Kannauj and Kashmir were prominent states among them. 
  • The feeling of nationalism among the Indians was almost absent.

Religious conditions : – 

  • The Hindus of the rural regions worshipped many gods and goddesses.
  • Idol worship was prevalent. Brahmans had the sole privilege of reading the Hindu scriptures.
  • Only the Brahmans had the right to attain salvation.

Legal rules and condition of Laws and Judicial system : –

  • It was necessary to write applications that mention points against the accused in order to get justice. Justice depended upon the witnesses and before conducting witnesses, it was necessary to take oaths. Also, there were arrangements for oral justice. 
  • Criminal law was very mild in India. The limbs of serious offenders were amputated. The Brahmanas were exempted from death punishment. If a Brahman murdered someone, he was required to repent through fasts, prayers and charity.

Taxation system : – 

King was not the owner of the land. He took land tax from the peasants at 1/6th of the produce. The Brahmans were exempted from the burden of paying taxes. 

 Source :  The University of Edinburgh 

Alberuni believed that people of Indian sub-continent were excellent philosophers, good mathematicians and astronomers but criticised the hypocrisy of Brahmins Scholars that despite of explaining the scientific values of ancient text they preferred misleading the masses and keep them steeped in ignorance and superstitious.

The statue of Al-Biruni in United Nations

Office, Vienna.

💙

Its Pathological Physiology ⬆️

review : jotsna jari

John Macleod   🔼

John James Rickard Macleod – 

(6 September 1876 – 16 March 1935)

He was a British biochemist & physiologist. 

He devoted his career to Carbohydrate Metabolism.

He is noted for his role in the discovery and isolation of  Insulin. 

For which he and Frederick Banting received the 1923 Nobel Prize in Physiology or Medicine.

🔺 John Macleod’s Book –

A NOTICE of an earlier edition of this work appeared in NATURE of December 18, 1919 (p. 389). That a new edition should be required in a year’s time shows that the book has been found to meet the purpose for which it was written. The opportunity has been taken to recast the section on the nervous system, which has been excellently done by Dr. Redfield adding to it an account of the fundamental principles of the physiology of muscle and nerve. These changes will add to the value of the book to those for whom it is primarily intended, particularly to the medical man who wishes to apply advances in physiology to his clinical practice. Recent work on such questions as the effects of deficient oxygen supply, on “vitamins,” on the capillary circulation, and on wound shock has been duly incorporated. A good account of the problem of the carriage of oxygen and carbon dioxide in the blood, still a disputed one, will also be found. Although the price of the book seems rather high, it may reasonably be held that good value is obtained. It might be worth consideration, however, whether the omission of some of the coloured plates would not enable a wider circulation to be ensured by a lower price. The further such knowledge as that contained in the book is spread, the better will it be for the advance of medical science and practice.

❤️ INSULIN :-

Insulin is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the INS gene.

It is considered to be the main anabolic hormone of the body.

It regulates the metabolism of carbohydrates, fats & protein by promoting the absorption of glucose from the blood into liver, fat & skeletal muscle cells.

Insulin : Available Structure

  🔺    Insulin :  First experiment on dog

In January 1922, the team performed the first successful clinical trial, on 13-year-old Leonard Thompson, and it was soon followed by others.

Diabetes: Its Pathological Physiology,1913

Macleod’s presentation at a meeting of the Association of American Physicians in Washington, D.C., on 3 May 1922 received a standing ovation.

At that time, demonstrations of the method’s efficiency drew huge public interest, because the effect on patients, especially children, who until then were bound to die, seemed almost miraculous. 

The pharmaceutical company Eli Lilly & Co. took over mass production, but without an exclusive license, as the patent was transferred to the British Medical Research Council to prevent exploitation.

❤️

Poetry : Invocation ⬆️

 Poet : Jotsna Jari

 .

 I had a dream…    I had to fly 

 There was my horse of aspiration 

 Life in the air today 

 is just wrapped in a melancholy tone.

 .

 Flowers bloom all around

 they have no fragrance

 Where the time is lost

 I can not find it.

 .

 Everything is not available

 Yet I will do the dream real in my heart 

 Ah…  I will make the dream 

 come true in work.

 .

 The mountain of pain 

 of losing everything…  

 hides me 

 The sky still calls me close.

💛

Стихотворение: Призыв ⬆️

 Поэт: Йотсна Яри

 .

 Мне приснился сон… Мне нужно было лететь

 Был мой конь стремления

 Жизнь в воздухе сегодня

 просто окутан меланхолическим тоном.

 .

 Цветы расцветают вокруг

 у них нет аромата

 Где время потеряно

 Я не могу найти это.

 .

 Все недоступно

 Тем не менее, я сделаю мечту реальной в моем сердце

 Ах… я сделаю мечту

 сбыться в работе.

 .

 Гора боли

 потерять все…

 прячет меня

 Небо все еще зовет меня близко.

❤️

कविता : मंगलाचरण ⬆️

 कवयित्री: जोत्सना जरी

 .

 मेरा एक सपना था…   मुझे उड़ना था

 मेरी आकांक्षा का घोड़ा था

 आज हवा में जीवन

 बस एक उदास स्वर में लिपटा हुआ है।

 .

 चारों ओर फूल खिलते हैं

 उनकी कोई सुगंध नहीं है

 जहां समय खो जाता है

 मुझे नहीं मिल रहा।

 .

 सब कुछ उपलब्ध नहीं है

 फिर भी मैं अपने दिल में सपना सच करूँगा

 आह…  मैं सपना बनाऊंगा

 काम में खरे उतरो।

 .

 दर्द का पहाड़

 सब कुछ खोने का…

 मुझे छुपाता है

 आसमान अब भी मुझे पास बुलाता है।

💜

কবিতা  :  আবাহন   ⬆️ 

কবি  :   জ্যোৎস্না জরি 

.

স্বপ্ন ছিল  উড়ান ছিল

ছিল সাধের ঘোড়া 

আজ বাতাসে  জীবন শুধু

বিষাদ সুরে মোড়া ।

.

ফুল ফুটেছে  চারদিকেতে

সুগন্ধ আর নেই

সময় কোথায়  হারিয়ে গেছে

পাই না খুঁজে খেই ।

.

সব কিছু তো  হয় না পাওয়া

তবু মনের মাঝে

স্বপ্নটাকে সত্যি করে

নেবই  নেব কাজে ।

.

সব হারাবার  ব্যথার পাহাড়

আড়াল করে রাখে

আকাশ তবু হাতছানি দেয় 

আমায় কাছে ডাকে ।

💙

نظم: دعا

 شاعرہ: جوتسنا جری


 .

 میں نے ایک خواب دیکھا تھا… مجھے اڑنا تھا۔

 وہاں میری امنگوں کا گھوڑا تھا۔

 آج ہوا میں زندگی

 بس ایک اداس لہجے میں لپٹا ہوا ہے۔

 .

 چاروں طرف پھول کھلتے ہیں۔

 ان میں کوئی خوشبو نہیں ہے

 جہاں وقت ضائع ہوتا ہے۔

 میں اسے نہیں پا سکتا۔

 .

 سب کچھ میسر نہیں۔

 پھر بھی میں اپنے دل میں خواب کو سچ کروں گا۔

 آہ… میں خواب بناؤں گا۔

 کام میں سچ ہو.

 .

 درد کا پہاڑ

 سب کچھ کھونے سے…

 مجھے چھپاتا ہے

 آسمان اب بھی مجھے اپنے پاس بلاتا ہے۔


💚

James Hutchison Stirling ⬆️

writer : jotsna jari

James Hutchinson Stirling(22 June 1820 – 19 March 1909) was a Scottish idealist  philosopher & physician. His famous work The Secret of Hegel  (1st edition, 1865, in 2 vols.; revised edition, 1898, in 1 vol.) gave great impetus to the study of Hegelian  philosophy both in Britain  and in the United States, and it was also accepted as an authoritative work on Hegel’s philosophy in Germany & Italy. The book helped to create the philosophical movement known as British Idealism.

 His famous work is…. 

“The Secret of Hegel ”.

Anyone can realise the extent of its author’s power and penetration. Through long years of study he mastered the meaning of that most difficult and most rewarding of modern writers on philosophy. At the end the result he had reached was returned in a torrent; in language the force and picturesqueness of which were only matched by the conviction every sentence breathed forth. The book embodies a result which is likely to be enduring. It will hardly be superseded, for it has the quality of the work of genius. Along the road it has travelled one cannot get any further.

Apart from the Gifford Lectures, Stirling’s other major works include: The Secret of Hegel (1865); Sir William Hamilton: Being the Philosophy of Perception (1865); a translation of Albert Schwegler’s Handbook of the History of Philosophy (1867); Text-book to Kant: The Critique of Pure Reason (1868); As Regards Protoplasm in Relation to Professor Huxley’s Essay on the Physical Basis of Life (1872); Darwinianism: Workmen and Work (1894); What Is Thought? Or The Problem of Philosophy by Way of a General Conclusion So Far (1900).

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Poetry  :  Dream Car ⬆️

Poet  :  jotsna jari

.

You said that if my chest hurts,

you will bring me

a whole day

leisure and the fountain of dream.

.

You said that when the moon goes out,

you will be the moon in bed

With your head on the star pillow

then you will sing some tunes…  .

.

You said that rose buds

will spread caress on lips

in sleep & waking up…

.

How much spring

has come and gone

I did not wake up

in your touch.

.

So the moon went out

because you didn’t keep your promise

The spring wind

is still stopped…  

.

Yet the dream car does not stop

The happiness of living

flies….   .

💚